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Thursday, April 16, 2020 | History

5 edition of New research on DNA damage found in the catalog.

New research on DNA damage

New research on DNA damage

  • 9 Want to read
  • 1 Currently reading

Published by Nova Science Publishers in New York .
Written in English

    Subjects:
  • DNA damage,
  • DNA Damage -- genetics,
  • Aging -- genetics,
  • Neoplasms -- genetics

  • Edition Notes

    Includes bibliographical references and index.

    StatementHonoka Kimura and Aoi Suzuki, editors.
    ContributionsKimura, Honoka., Suzuki, Aoi.
    Classifications
    LC ClassificationsQH465.A1 .N49 2008
    The Physical Object
    Paginationp. ;
    ID Numbers
    Open LibraryOL16798229M
    ISBN 109781604565812
    LC Control Number2008017044
    OCLC/WorldCa213848806

    Given that damage to DNA can lead to cancer, understanding how SUMO proteins are involved in DNA repair could yield clues in the hunt for new cancer treatments. Two new papers published today in the journal Nature, from researchers funded by Cancer Research UK and the Breast Cancer Campaign, help to unravel the mystery of SUMOs’ involvement. Or you just read it over and over for years, dog-earing pages and stuffing the book in backpacks and totes (again, me). It can end up looking like this: The same thing sort of happens to your DNA. In a cell, damage and multiple reads can affect both the actual words (genes), but also the paper (the chromatin that organizes DNA).


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New research on DNA damage Download PDF EPUB FB2

This book is intended for students and scientists working in the field of DNA repair. Select topics are presented here to illustrate novel concepts in DNA repair, the cross-talks between New research on DNA damage book repair and other fundamental cellular processes, and clinical translational efforts based on paradigms established in DNA repair.

The book should serve as a supplementary text in courses and Cited by: 9. DNA damages give rise to mutations and epimutations that, by a process of natural selection, can cause progression to cancer. First, we describe the distinguishing characteristics of DNA damage, mutation and epimutation.

DNA damage is a change in the basic structure of DNA that is not itself replicated when the DNA is by: ISBN: OCLC Number: Description: xvi, pages: illustrations (some color) ; 26 cm: Contents: Cancer and aging as consequences of un-repaired DNA damage / Harris Bernstein, Claire M.

Payne, Carol Bernstein --Radiation-induced DNA damage responses as novel targets in cancer treatments / Wei-Dong Wang, Zheng-tang.

Online shopping for Books from a great selection of Biological Sciences, Nature & Ecology, Mathematics, Earth Sciences, Physics, Chemistry & more at everyday low prices. DNA News and Research RSS. have discovered a new anti-phage defense mechanism found in some bacteria, which uses previously unknown features to protect their DNA.

DNA damage and inaccurate. ISBN: OCLC Number: Description: xiii, pages: illustrations (some color) ; 27 cm: Contents: Molecular targeting of DNA repair: a means to improve therapeutic index / Spencer J. Collis --DNA repair and lung cancer / Chikako New research on DNA damage book, Koichi Takayama, and Yoichi Nakanishi --Comet assay as a tool to evaluate DNA repair.

Books shelved as dna: The Double Helix by James D. Watson, DNA: The Secret of Life by James D. Watson, The Family Tree Guide to DNA Testing and Genetic G. The researchers would have to extract the DNA-like stuff from the fossil and try to read its chemical code in order to definitively confirm whether or not it’s DNA, but based on.

A group of researchers, lead by Vasily M. Studitsky, professor at the Lomonosov Moscow State University, discovered a new mechanism of DNA repair, which opens up new perspectives for the treatment.

Progress in DNA Damage Research [Souta Miura, Shouta Nakano] on *FREE* shipping on qualifying offers. This title presents the latest research on DNA damage, which due to environmental factors and normal metabolic processes inside the cell.

Experts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches.

This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs. Knowledge of DNA repair mechanisms advances with new research Date: Source: Mayo Clinic Summary: We humans like to think our DNA is well-protected in the nucleus of each cell.

The journal welcomes articles describing databases, methods and new technologies supporting research on DNA repair and responses to DNA damage. Letters to the Editor, hot topics and classics in DNA repair, historical reflections, book reviews and meeting reports also will be considered for publication.

This major new treatise provides the reader with up-to-date critical surveys of every important area of research on DNA damage and the repair mechanisms in each major system currently under investigation.

Authoritative and timely, DNA Damage and Repair is certain to become the new standard reference and resource in the field. New Research Shows DNA Can Be Altered by Trauma, Passed On to Offspring both in New York, studied the genetics of 32 Jewish men and women who had experienced the horrors of persecution during Author: Carly Okyle.

Types. Damage to DNA that occurs naturally can result from metabolic or hydrolytic processes. Metabolism releases compounds that damage DNA including reactive oxygen species, reactive nitrogen species, reactive carbonyl species, lipid peroxidation products and alkylating agents, among others, while hydrolysis cleaves chemical bonds in DNA.

Naturally occurring oxidative. DNA damage occurs frequently to cells as a result of normal cellular processes, but one of the worst genetic malfunctions that can occur is DNA double-strand breaks, or DSBs.

This can lead to cancer and increased resistance to cancer therapy. New research from scientists at The University of Texas MD Anderson Cancer Center reported their findings regarding histone.

Researchers uncover new instruction manual to repair broken DNA Date: June 8, Source: Drexel University Summary: Researchers have discovered how the Rad52 protein is a crucial player in RNA. Her research interests are focused on computer modeling of DNA lesions, with the goal of elucidating the molecular origins of their mutagenic and tumorigenic properties.

She holds a PhD degree in physical chemistry with a minor in physics from the Polytechnic Institute of New York, and has published over papers in peer-reviewed journals. DNA Damage - Science topic Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result.

DNA Damage Response. and it is the hallmark of a cell with a defect in the ATM/Chk2/cdc25A axis. An active area of DNA repair research is the identification of other CHK1 and CHK2 phosphorylated substrates.

View chapter Purchase book. Read full chapter This is a critical phase as this is when the cell synthesizes the new DNA and. A group of human nuclei with fluorescently labeled genome (green) and induced DNA damage (red).

Credit: Jonah A. Eaton and Alexandra Zidovska, Department of Physics, New. Increased brain growth, mutations and autism linked in new study. Salk Institute researchers have now found a pattern of DNA damage that is unique to brain cells derived from individuals with a.

Cells constantly incur damage to DNA. Unrepaired damage can lead to problems during DNA replication. Van Houten explained that "DNA is the only biomolecule that has dedicated repair pathways." Interestingly, Van Houten worked with Aziz Sancar, M.D., Ph.D., who received the Nobel prize for chemistry inin recognition of his work on DNA repair.

The variable response in DNA damage levels and individual differences in DNA repair efficiency suggest a susceptible subgroup of people probably with Author: Daniel Yarosh. DNA damage is thought to threaten the gene pool and can sometimes cause various diseases, such as neurological disorders and certain cancers.

In a new study published in the online journal Nature Communications, University of Utah chemists have created a new way to find chemical damage. Recognition, Repair and Signalling of DNA Damage (CR-UK DNA Repair Enzymes Research Group) SIngle Strand Break Repair We are studying the structural basis for recognition and repair of DNA single-strand breaks and gaps by PARPs and the PARP1/XRCC1 SSBR system.

Understanding how metal complexes interact with DNA has become an active research area at the interface between chemistry, molecular biology and medicine. Metal Complex - DNA Interactions provides a comprehensive overview of this increasingly diverse field, presenting recent developments and the latest research with particular emphasis on metal.

UNSW medical scientists have discovered that DNA repair is compromised at important regions of our genome, shedding new light on. Featuring more t references and a text lavishly complemented by over illustrations, DNA Repair and Mutagenesis, 2nd Edition, is a timely update to the original edition published in The addition of three new authors, including an expert in the field of structural biology, ensures a comprehensive review of the most current research in diverse subject by:   The book integrates a lot of new studies – from genetics, epidemiology and social science – that have been accumulating.

We also provide a new biological underpinning to the mind-body : Zoë Corbyn. DNA Damage and Repair Mechanisms. Damage to cellular DNA is involved in mutagenesis and the development of cancer. The DNA in a human cell undergoes several thousand to a million damaging events per day, generated by both external (exogenous) and internal metabolic (endogenous) processes.

Many Americans have made a New Year’s resolution to improve their health, and protecting part of your DNA – the telomere – might help you reach that goal. In the book “The Telomere Effect.

apoptosis, cancer rates, cancer research, dna damage, elephants, genetic research, leukemia inhibitory factor, lif6, mitochondria, p53 genes New Findings About Cancer Gene Recently the news spread that elephants have times the amount of a cancer suppressing gene, called p DNA damage analysis, DNA repair assays, and mutation detection are a few of the techniques featured.

Chapters present detailed experimental protocols benefiting researchers and students in the fields of toxicology, biotechniques, molecular biology, photobiology, medical genetics, and. Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, offering broad integrated coverage that will help researchers understand the important functional relationships among different DNA repair pathways, as well as the relationships among DNA.

The book is an impressive chronicle of what genetic research over the last few decades has done to complement the story of evolution, a tale once told. Find many great new & used options and get the best deals for Contemporary Cancer Research: DNA Damage and Repair: Volume 2: DNA Repair in Higher Eukaryotes (, Paperback) at the best online prices at eBay.

Free shipping for many products. Drexel University and Georgia Institute of Technology researchers have discovered how the Rad52 protein is a crucial player in RNA-dependent DNA repair.

The results of their study, published today. The genomic integrity of every organism is constantly challenged by endogenous and exogenous DNA-damaging factors. Mutagenic agents cause reduced stability of plant genome and have a deleterious effect on development, and in the case of crop species lead to yield reduction.

It is crucial for all organisms, including plants, to develop efficient mechanisms for maintenance of Cited by:. 4. DNA Damage and DNA Repair. DNA damage occurs continuously in all organisms via a number of endogenous and exogenous factors, and it seems to play a central role in many biological processes, ultimately leading to cancer (Figure 5).

Hence, robust DNA repair systems, which repair this damage, have evolved to maintain genomic by:   To demonstrate the potential usefulness of the new system, the researchers evaluated three compounds that have been proposed as potential inhibitors of DNA repair. Such compounds could be used to boost the effectiveness of chemotherapy agents by preventing cancer cells from repairing the DNA damage caused by chemotherapy.

Kary B. Mullis, a biochemist who won the Nobel Prize in Chemistry for discovering a way to analyze DNA easily and cheaply and thus pave the way for major advances in medical diagnostics.